Aniline is an organic compound with the formula C 6 H 5 NH 2. Specifically, it is used to treat methemoglobin levels that are greater than 30% or in which there are symptoms despite oxygen therapy. Some boots which had been dyed black eight days before, but had been kept in a closed box, originated an acute case of aniline poisoning. 1988; 26(5-6):357-64 (ISSN: 0731-3810) Mier RJ. ACUTE ANILINE POISONING TREATED BY HEMODIALYSIS. 1) Aniline is a skin and eye irritant and a mild dermal sensitizer. Drug overdoses cause a range of symptoms, including excitability, sleepiness. [emedicine.medscape.com], Because phosgene is poorly soluble in water, it reacts minimally with oropharyngeal and conducting airway tissues and as a result can penetrate deeply into the lung, where it exerts its effects at the alveolar-capillary membrane (see Pathophysiology). Anticholinergic substances. This page is not available in your area. [flipper.diff.org], The symptoms of methemoglobinemia differ depending on the concentration level of MetHb in the blood, with 0–20% potentially producing cyanoderma; 20–40% potentially producing headache, anxiety, vertigo, and a frequent pulse; 40–60% potentially producing The goal of treatment is to remove the alcohol from your body and to keep your organs working properly. UNII-SIR7XX2F1K. Treatment List for Chemical poisoning -- Aniline. Use of alcoholic beverages enhances the harmful effect. There has been considerable disagreement as to the value of methylene blue in combating this disorder. 1978. [slideshare.net], […] coal-tar benzol cold curing compounding room containing crimson antimony cyanosis described dipping room disease dizziness employed exhaust exposed exposure floor footwear gastric juice German girls gloves golden antimony golden sulphide grain handle headache UN 1547. Glucagon. [amboss.com], […] for short periods of time decreases the ability of blood to carry oxygen .Lack of oxygen causes effects ranging from severe headache, nausea, sometimes vomiting, to dryness of throat and loss of appetite Central nervous symptoms: confusion, ataxia, vertigo REPORT OF A CASE. Are any future health effects A single small exposure from which a person recovers quickly is not . Treatment of any poisoning begins with the restoration of airway patency, stabilization of breathing and circulation. Clin Pharm 1992; 11: 800-5. Treatment is supportive for most poisonings; specific antidotes are necessary for a few. [ch.ic.ac.uk], In acute poisoning aniline in mild cases, victims complain of weakness, dizziness, headache pain ; marked blueness of the lips, ears, nail phalanxes; in the blood metgemoglobin killed Ganza. Aniline (and salts) Aniline and homologs. [flipper.diff.org], Dapsone-induced methemoglobinemia and hemolytic anemia. It has previously been used for cyanide poisoning and urinary tract infections, but this use is no longer recommended. NCI-C03736. Emergency treatment should begin before the physician arrives. Mier, RJ. Toxin. To manage chemically induced methemoglobinemia properly, a clinician must be aware of its pathophysiology, be adept with the use of reducing agents such as … Its main use is in the manufacture of precursors to polyurethane, dyes, and other industrial chemicals. The toxic agent was identified as aniline by GC with mass selective detection after organic solvent extraction and 11 h after ingestion the plasma aniline level was 0.13 mg/l. The Hague, The Netherlands. (1,6) The chemical formula for aniline is C 6 H 7 N and the molecular weight is 93.12 g/mol. Symptoms vary, but certain common syndromes may suggest particular classes of poisons. Mier RJ(1). Aniline and homologues. 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